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The most important practical distinction is pathway: CJC-1295 / Sermorelin / Tesamorelin: GHRH receptor pathway Ipamorelin / GHRP-2 / GHRP-6 / Hexarelin / MK-677: ghrelin or GHSR pathway HGH / GH: direct hormone, not a secretagogue This is why CJC-1295 and Ipamorelin are often studied together: they represent complementary upstream signals into GH-axis biology

Conversely, OTC drugs are frequently limited by their milder efficacy and regulatory constraints, which restrict their use for more severe or complex obesity cases

Energy production at the cellular level

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