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The new #APIC_Best_Practices_Guide (Version 2 March 2024) provides a comprehensive framework for: Supplier selection and qualification Continuous monitoring of performance and risks Managing quality agreements and audits Even termination of collaboration in critical situations Based on a risk-based approach (#ICH Q9), this guideline supports API manufacturers to: Ensure quality and regulatory compliance Identify and control supply chain risks (quality, legal, business continuity) Build reliable and sustainable supplier partnerships through an integrated approach Notably, the four stages of the supplier management lifecycle (Selection, Qualification, Operational, Termination) and the central role of the Quality Unit are emphasized as key elements in this new version
Because of this profound cellular mechanism, immense public interest has been generated regarding its systemic utility
J Neurosurg 2025
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