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The SELECT trial, published in 2023, enrolled 17,604 adults with overweight or obesity and established cardiovascular disease but without diabetes

Practical prevention strategies include: Use a medication diary or smartphone app to record each injection, including date, time, and dose Set a weekly reminder on your phone for the same day and approximate time each week Mark your calendar immediately after each injection Store Ozempic in a consistent location and check the pen before each use to confirm the correct dose setting Read the pen label carefully before injection, as different strengths are available The Ozempic pen design includes dose selection features, but errors can still occur: Always visually confirm the dose in the dose counter before injecting Follow the Patient Information Leaflet instructions exactly for pen use Never attempt to split doses or take partial weekly amounts more frequently If you miss a dose , follow the manufacturer's recommendations: Take the missed dose within 5 days of when it was due If more than 5 days have passed, skip the missed dose and resume your normal schedule Never double up to compensate for a missed dose Additional safety measures: Keep Ozempic in its original packaging with clear labelling If you have vision problems, ask a family member or carer to help verify doses Attend regular diabetes reviews where your healthcare team can assess your injection technique Report any confusion about dosing to your GP or diabetes specialist nurse immediately For patients managing multiple injectable medications, consider using different injection sites or times of day for each medication to reduce confusion

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Missing doses can affect your weight loss trajectory and may cause temporary return of appetite