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Studies indicate that 25 to 40 percent of weight lost on GLP-1 agonists can be lean mass, including muscle tissue
Animal experiments also suggest that liraglutide has a neuroprotective effect in murine models of Parkinson's disease (PD), which is accomplished by activating PGC-1 to regulate mitochondria biogenesis, dynamics, autophagy, and apoptosis in substantia nigrathe region in the brain that gets damaged by PD [22]
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