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Your body needs time to adjust to each: GLP-1 receptor: Slows gastric emptying, reduces appetite GIP receptor: Enhances insulin signaling, affects fat metabolism Glucagon receptor: Increases energy expenditure, promotes fat oxidation Jumping to high doses overwhelms these systems, causing: Severe nausea and vomiting Treatment discontinuation Longer overall time to reach therapeutic doses The data: In the Phase 2 NEJM study, participants who started at 4 mg instead of 2 mg had significantly higher rates of gastrointestinal side effects
A person must provide accurate health information and complete an evaluation before a licensed provider decides whether a prescription is suitable
As evidence matures, it is anticipated that clinical guidelines will be developed to support safe and effective use of retatrutide, should it receive regulatory approval
Initial Evaluation Your journey towards medical weight loss begins with an initial evaluation conducted by Dr
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