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At the standard escalation of 2.5 mg for 4 weeks then 5 mg, you would use 10 mg in the first month (4 doses at 2.5 mg) and then continue at 5 mg per week
Both pairs are consistent with the borrowed exponent, but neither is a clean test: in both, the lighter arm is also the higher-starting-dose arm, so body weight and titration path are collinear and the comparison cannot separate them
includes sample validation
If the skin feels tight against bone (common directly over the kneecap), move 2-3 cm laterally until you can pinch a fold
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