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Gene expression data (human): Even without long-term outcomes data, human scalp studies show that topical GHK-Cu activates genes involved in follicle cycling within weeks of application

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Critical safety considerations for laboratory use include potential immunogenicity concernswith peptide therapeutics commonly showing injection site reactions (20-40% with subcutaneous administration) and possible antidrug antibody formationalong with theoretical concerns that pro-angiogenic properties could potentially influence experimental tumor models, requiring appropriate controls in oncology-related research

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