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Tesamorelin is an FDA-approved synthetic GHRH analog used to reduce visceral fat in HIV-associated lipodystrophy and reliably increases GH and insulin growth factor 1 (IGF-1)

Given the potential role of GSH in the regulation of immune functions 43,44 and the distinct expression of Gclc in mature B cell subsets, we studied FoB and MZB activation in the presence of buthionine sulfoximine (BSO), a Gclc inhibitor 45

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Glutathione reductase-catalyzed cascade of redox reactions to bioactivate potent antimalarial 1,4-naphthoquinones--a new strategy to combat malarial parasites