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As a result, these microbial metabolites not only shed light on the gut-immune axis in PD pathogenesis but also provide potential non-invasive biomarkers for disease diagnosis, stratification, and progression monitoring
Hexarelin has been documented to produce more pronounced GHS-R1a desensitization in rodent studies, particularly with sustained or high-frequency administration protocols
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In contrast, GSH depletion drives M1 polarization, resulting in heightened secretion of pro-inflammatory cytokines, including TNF-, IL-6, and IL-1 (Kwon et al., 2019)
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