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Regulation of intestinal proglucagon-derived peptide secretion by glucose-dependent insulinotropic peptide in a novel enteroendocrine loop
Bhatwa A, Wang W, Hassan YI, Abraham N, Li XZ, Zhou T
A 2024 meta-analysis (Sattar et al., Lancet Diabetes Endocrinol) found that switching from semaglutide to tirzepatide produced an additional 4.2 kg mean weight loss over 40 weeks, even when semaglutide had been titrated to maximum dose
When layered onto Retatrutides metabolic effects, this healing support addresses the collateral demands of rapid weight loss
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