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In studies using perfused pig and rat pancreata, researchers in Denmark and the US described potent insulinotropic (10, 11), and glucagonostatic (12) effects in vitro , while studies in healthy humans revealed that circulating levels of GLP-1 increased after nutrient intake and confirmed GLP-1 to be an incretin hormone in vivo (13)
The makers of Ozempic state that the safety of this drug to unborn children is not known
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