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At baseline, mean age and the proportion of subjects with heart failure and prior CV events were higher, and mean eGFR was lower, in the SUSTAIN 6, PIONEER 5 and PIONEER 6 trials than in the other trials
And heat above 30 degrees Celsius (86 degrees Fahrenheit) is universally bad regardless of formulation type
10.1373/clinchem.2005.057638 107
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