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For example, 2D cultures only allow interactions with neighboring cells and the formation of cell-ECM adhesions on the substrate side in the horizontal plane, whereas in 3D culture, cells are capable of forming adhesions on all sides in a dynamic way [239]
Rather than targeting a single function, it influences several processes involved in aging and tissue repair
They can contribute to modest body-composition changes, typically reducing visceral fat and improving muscle tone over 2 to 3 months of use
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