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Some small studies have suggested it might provide benefits similar to retinoids while causing less irritation
By mediating the transcription of crucial antioxidative enzymes, FOXO4 may help mitigate oxidative stress and maintain cellular integrity and function during episodes of high oxidative load or inflammation
However, the exact mechanism between Tregs and ER stress in the pathogenesis of vitiligo remains to be investigated
Further research should assess the balance between its potential benefits and risks, particularly in patients with concurrent infections or immunocompromised states
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