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Acidic pHresponsive siRNA conjugate for reversible carrier stability and accelerated endosomal escape with reduced IFNassociated immune response

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First, using HPLC and HPLC-associated radioactive detector, we identified six radioactive components, in addition to prototype [ 3 H]BPC157, in rat plasma collected at 0.05, 0.167, 1, 8, and 24 h after administration (Supplementary Figure S1)

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