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Strength training: Engage in regular strength training, ideally 2-3 times per week, focusing on compound exercises that work multiple muscle groups
Participants also recorded reductions in waist circumference (average 7.1cm loss on 6mg, 8.2cm on 12mg, 10cm on 36mg, compared with 3.1cm loss on placebo), blood pressure (estimated -4.2 and -1mm HG difference between placebo and orforglipron in systolic and diatolic blood pressure, respectively) and cholesterol (-2.1% difference between placebo and orforglipron)
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10.1016/S1474-4422(21)00061-2 147 WangY.XuH.FuQ.MaR.XiangJ
New Study Highlights Superiority of Bariatric Surgery Over GLP-1 Medications for Sustained Weight Loss A new real-world study presented at the ASMBS 2025 Annual Meeting compares outcomes between GLP-1 medications (such as semaglutide and tirzepatide) and bariatric surgery
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