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Studies show GLP-1 receptor agonists can help reduce body weight by 5-15% when combined with lifestyle modification, though menopause-specific outcomes require individualized assessment

NICE guidance recommends reviewing patients at regular intervals to assess treatment response, tolerability, and the need for dose adjustments or additional interventions

The evidence suggests that without deliberate intervention, patients on GLP-1 therapies may lose a significant proportion of their weight from lean mass, a finding that has considerable implications for long-term metabolic health, physical function, and the sustainability of results. Why Muscle Mass is Not a Cosmetic Concern When patients hear the phrase muscle loss, they frequently interpret it through an aesthetic lens

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