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Yes, and many users eventually make this transition

GLP-1 and GIP are two peptide hormones that play a role in insulin secretion , appetite regulation, and gastric emptying (the process in which food leaves your stomach and enters the small intestine)

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While many people tolerate the drugs without psychological symptoms and there is no conclusive evidence the effects are permanent, physicians caution that rapid weight loss, shifting body image and changes in brain chemistry together may affect mental health raising new questions about long-term risks as prescriptions continue to surge