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Appetite suppression and weight loss may mask eating disorder symptoms, delay diagnosis, and reinforce stigma, particularly for patients in larger bodies
Research on the traits of gut microbiota in T2DM patients who are either tolerant or intolerant to metformin showed that alterations in gut microbiota composition following metformin therapy play a role in drug intolerance (Daz-Perdigones et al., 2022)
The 13% who discontinued did so primarily during weeks 4-10 when gastrointestinal side effects peak
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