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Dysfunctions in neurotransmitter signaling, affecting cholinergic and dopaminergic pathways in particular, have been involved in the occurrence of cognitive impairments
The expansion of BMAT under conditions such as caloric restriction may also play a role by altering the bone marrow niche and inhibiting osteoblastogenesis through adipocyte-derived cytokines
doi: 10.1016/j.physbeh.2007.02.012 154 TilakaratneNChristopoulosGZumpeETFoordSMSextonPM
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