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as the respondent
They were fasted overnight and then weighed
Persistent Gastrointestinal Issues: If nausea, vomiting, or diarrhea persists for several days despite following a balanced meal plan and staying hydrated, seek medical attention
What persists is the downstream melanogenesis cascade: once MC1R is activated on melanocytes, those cells continue producing eumelanin through enzymatic pathways (tyrosinase, TYRP1, DCT) that don't require continuous peptide presence
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