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To maintain progress achieved through GLP-1 agonist therapy, continuous dedication to lifestyle interventions is necessary rather than just an initial attempt at improvement

Glucagon-like peptide-1 receptor agonists and risk of bone fracture in patients with type 2 diabetes: A meta-analysis of randomised controlled trials

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The SURPASS-J-combo trial embraced diabetic adults with HbA 1c 7% to 11% and BMI 23 kg/m 2 , stable weight and uncontrolled with therapy of metformin, thiazolidinedione, sulfonylureas, meglitinide, alpha-glucosidase inhibitor or SGLT2-i (81)