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Introduction Pancreatic ductal adenocarcinoma (PDA), or pancreatic cancer, is a devastating exogenous pancreatic disease that ranks the fourth leading cause of cancer mortality and is projected to be the second leading cause of death by 2030 in the United States (Rahib et al., 2014

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All doses markedly suppressed food intake compared to vehicle controls, with the 30 and 300 nmol/kg doses producing the strongest anorectic effects, reducing 24-hour food intake by 51% and 57%, respectively

This is the result of the very high GH sensitivity of a liver expressing high levels of GHRs