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Commercial Insurance: Coverage, Copays, and Savings Card Details Tirzepatide is available as Zepbound, which is FDA approved for chronic weight management in adults with obesity or overweight plus a related condition like high blood pressure, type 2 diabetes, or high cholesterol
Risks to the Pancreas Both medications carry a small risk of pancreatitis, which is inflammation of the pancreas
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HR 1.19, 95% CI 0.91.58), but not for the other DPP-4 inhibitors as in the TECOS study for sitagliptin (HR 1.00, 95% CI 0.831.20) or the CARMELINA study for linagliptin (HR 0.90, 95% CI 0.741.08) (57, 62, 64, 65, 68)
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