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Some patients experience therapeutic benefitsincluding weight loss and improved blood glucosewithout significant nausea or other side effects, particularly when dose escalation follows the recommended gradual schedule

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found that both UC and CD patients with DM2 presented a reduced risk of surgery when treated with GLP-1 RAs compared to other hypoglycemic agents ( With regard to safety concerns, the most prevalent adverse effects associated with GLP-1 RAs are gastrointestinal, such as bloating, dyspepsia, nausea, vomiting, diarrhea and constipation (108)

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