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Several studies, such as the SUSTAIN and PIONEER trials, highlight these side effects associated with the use of semaglutide
the median BMI was 37.0 kg m 2 (33.7, 41.4) at baseline, 180 (34.0%) had class I obesity, 171 (32.3%) had class II obesity and 178 (33.7%) had class III obesity
Over 89% of participants at this dose level lost at least 5% of their body weight, and a substantial proportion lost 20% or more
Appetite returns progressively across that window rather than all at once
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