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The skin quality and nutritional status are usually poor so techniques used have to address the risk of recurrence and incision dehiscence
In previous studies, cellular senescence has been considered a mechanism of preventing abnormal proliferation to malignancy in keloids and could be used to halt the progression of keloids 13
For example, in breast cancer, autocrine expression of GH from the tumor cells promotes a more aggressive cellular phenotype, compared to exogenously added GH, which mimics endocrine secretion
That's why time and temperature, not visual inspection alone, are the primary safety checks
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