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Questo aminoacido svolge un ruolo importante nel metabolismo energetico delle cellule , favorendo il trasporto degli acidi grassi a catena lunga all'interno delle cellule, dove possono essere metabolizzati per produrre energia
In Eli Lillys Phase 2 trial published in NEJM in 2023, participants on the highest dose (12 mg weekly) lost an average of 24.2% of their body weight over 48 weeks
The drug does not cause birth defects or premature birth, but it does increase the risk of a baby being born with pulmonary hypertension or poor adaptation
Wu G, et al
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