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However, the long-term treatment with GLP-1RAs may reduce the insulin levels in both T2DM (122) and prediabetic patients (123), owing to the glycemic normalization and increased insulin sensitivity in these patients
b , Overlay of GPCR transmembrane bundles in the activated GLP-1R complex and T4L- 2 ARG s Nb35 complex shown in light green and grey, respectively
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Current Pharmaceutical Design, 20(7), 1126-1135
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