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The lower concentration allows for more precise dosing at lower doses during the titration phase
FDA prescribing information, Mounjaro (tirzepatide) injection, BLA 215866: approved indications, once-weekly 2.515 mg titration, ~5-day half-life, boxed warning for thyroid C-cell tumors
These therapies hold promise as nonspecific immunomodulators, offering new approaches to regulating gut microbiota composition and potentially predicting patient responses to treatment
Neuropsychopharmacology 44 , 10361042 (2019)
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