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Cyclooxygenases and the prostaglandins they form also have roles beyond inflammation
Conclusions Together, this review highlights peripheral inflammation and misfolded alpha-synuclein as pivotal contributors to neuroinflammatory mechanisms in Parkinson disease, emphasizing monocyte-related pathways as promising targets for disease monitoring and intervention
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However, challenges persist, and further research is necessary to address unmet needs in early detection and screening, develop more effective and personalized therapeutic strategies, and further elucidate the molecular underpinnings of EC
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