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Degeneration of dopaminergic neurons in the substantia nigra pars compacta, which projects to the basal ganglia and the striatum, is the hallmark of PD
Lack of education about the risks
Among the evolved AIH research models such as Concanavalin A (Con A), lipopolysaccharide (LPS) and LPS with d-galactosamine (GalN)-induced models, Con A animal is the most used model and for induction of AIH, because Con A-induced hepatitis model possesses a remarkable change in transaminase level, inflammatory cytokines and immune cells
Cartoni, C
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