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Same incretin pathway Little added efficacy More cost More polypharmacy Rule in practice: stop DPP-4 inhibitor before starting semaglutide unless there is a very unusual reason not to
Special thanks to Jess, Gina, Charles, and Dr
Patients should seek immediate medical attention if dark urine occurs with severe abdominal pain, persistent vomiting, signs of severe dehydration, or fever
Dose titration starting low and increasing gradually substantially reduces side effect severity
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