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Together with the broader body of evidence from the STEP programme, the trial reinforces the role of semaglutide as a key component of modern cardio-kidney-metabolic (CKM) management, complementing guideline directed heart failure therapies and supporting a shift toward comprehensive treatment of obesity, diabetes, and HFpEF rather than focusing solely on glycaemic control
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Tissues for analysis were snap frozen in liquid nitrogen and stored at 80C
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