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Novo Nordisk last month announced it plans to expand its oral biologic pipeline, investing $2.1 billion with Vivtex Corporation , which includes obesity therapy Wegovy (semaglutide)
Of note, glycemic control improved with HbA1c reductions reaching 0.8% with survodutide therapy, indicating preserved glycemic benefits despite GCG agonism, likely reflecting the predominant GLP-1 receptor activity ratio
That work led to the discovery of glucagon-like peptide-1 (GLP-1), a hormone released from the small intestine that helps control insulin secretion, slow digestion and reduce appetite
Chen, S., Yue, T., Huang, Z., Zhu, J., Bu, D., Wang, X
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