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p53 binds to the promoter of SCD1 and suppresses its transcription
Functional sepiapterin reductase is a homodimeric enzyme which first converts 6-pyruvoyltetrahydropterin to 1-hydroxy-2-oxopropyltetrahydropterin, which is then reduced to 1-oxo-2-hydroxypropyltetrahydropterin, and then finally to 5,6,7,8-tetrahydrobiopterin, BH 4
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