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Early detection and treatment can improve the prognosis, but neuronal damage can be irreversible [4]
GLP-1 itself exemplifies this phenomenon, as early native peptide formulations required continuous infusion to achieve sustained efficacy
In one published case, an active, lean-adjacent man lost about one-third of his total weight as muscle on 2.5 mg and recovered it after adding resistance training and increasing protein. This is a cautionary case, not an incidence estimate
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