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5 correlate inversely with the reactivities and k ox values for the same residues of the reverse reactions in Fig

The MSEL is a developmentally integrated system that assesses language, motor, and perceptual abilities for children aged from birth to 68 months of age ( Behavioral concerns were measured by the Child Behavior Checklist 1-5 Language Development Survey (CBCL)

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A structure-based assignment of the glutathione activator site without transition-state analogues is much more difficult because of labile GSH interactions 2 that likely depend not only on the presence of the first glutathione moiety but also on conformational changes of the glutathionylated enzyme 3,12,37,44