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The role of glucagon-like peptide-1 in reproduction: from physiology to therapeutic perspective
For example, in colorectal cancer (CRC), tumor-derived lanosterol can be taken up by CD8 T cells, where it suppresses the mevalonate pathway and reduces prenylation and activity of KRAS proto-oncogene, GTPase (KRAS), ultimately promoting T cell apoptosis and impairing their antitumor function
By contrast, the proliferation of normal melanocytes was reduced in response to autophagy inhibition only after 96 h of treatment
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