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Some individuals may experience mild digestive symptoms like bloating or gas during the first few days of use as their gut bacteria adjust
this is probably due to the high CMFDA fluorescence in the perinuclear area, which could be explained by the fact that BSO, at the concentrations used in this work, is unable to deplete mitochondrial GSH [34], [35]
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Accordingly, the macrophage / -cell crosstalk can dictate autoimmunity and -cell destruction, or conversely, immune tolerance and preservation of -cell mass and function
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