Significantly downregulated proteins when adjusting for body weight effects in STEP 1 known to be associated with CVD risk included tenascin C (TNC), NT-proBNP, thrombospondin 2 (THBS2), complement component C1q receptor (cluster of differentiation 93 (CD93)), macrophage scavenger receptor 1extracellular domain (MSR1) and angiopoietin-2 (ANGPT2)
Rajeswaran FRCP(UK);MSc Consultant Physician Obesity, Diabetes & Endocrinology Dr Rajeswaran is a Consultant Physician, Specialist in Endocrinology, Diabetes and Obesity
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Ongoing research includes clinical trials focused on evaluating the efficacy and safety of Semaglutide in various IBS subtypes, its long-term impact on gastrointestinal and metabolic health, and its interaction with the gut microbiome