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GLP-1 medications bind to and activate the GLP-1 receptor in the brain, pancreas, gut, heart, liver, kidneys and blood vessels, triggering a wide range of beneficial metabolic effects. Meanwhile, tirzepatide is a dual GIP/GLP-1 receptor agonist that targets both GIP and GLP-1 receptors
Polyphenols Polyphenols are secondary metabolites of plants with antidiabetic effects, whose benefits are related to the stimulation of insulin and GLP-1 secretion, as well as increasing GLP-1 half-life by inhibiting DPP-4 activity [187]
Semax is a synthetic peptide created in Russia
Epidemiology studies of IR Sex difference Different investigations have indicated that premenopausal women exhibit many less metabolic disorders than men, including lower incidence of IR, although this effect diminishes severely when women reach the postmenopausal situation
