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Diabetic neuropathy and metabolic effects (Phase 2): A 2015 Phase 2 trial published in Molecular Medicine (Brines et al.) evaluated ARA-290 in type 2 diabetes patients
One unresolved question in ALS is why the neurons most susceptible to the altered/deficient EAAT2 (and neurodegeneration) come from two different populations which do not have much in common: The lower motor neurons in the spinal cord are cholinergic and project peripherally while the upper motor neurons are glutamatergic, excitatory, reside in the cerebral neocortex and target the brain stem and spinal cord (corticobulbar and corticospinal tracts)
However, its important to note that Ozempic can have side effects, such as nausea, vomiting, and diarrhea
These medications are included in the GLP-1 receptor agonist family of drugs
