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Unlike other antioxidants that you must get solely from your diet, your body is designed to manufacture its own supply of glutathione

Melatonin ameliorates trimethyltin chloride-induced cardiotoxicity: the role of nuclear xenobiotic metabolism and Keap1-Nrf2/ARE axis-mediated pyroptosis

Decreased glutathione levels, ROS accumulation, and increased inflammatory cytokines trigger follicular cell damage, apoptosis, and an autoimmune response (Lopes et al., 2022)

This is because issues with regular function of the gastrointestinal tract can prevent the proper release and absorption of the vitamin, which can cause a deficiency if not supplemented properly