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Ozempic and other GLP-1s signal to those receptors, making you feel less hungry, he says

However, controversy exists regarding whether these effects are mediated through the direct effects of GLP-1RA targeting intrahepatic cells

In studies of Ozempic for type 2 diabetes, 20.3% of participants taking a 1-milligram (mg) dose of Ozempic reported feeling nauseous, compared to 6.1% of those given a placebo