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& Drexler, H
AOD9604 has been characterised across pre-clinical, safety pharmacology, and early-phase clinical research since the late 1990s, with peer-reviewed publications spanning lipid metabolism, adipose biology, joint repair, and bioavailability
Yang and Stockwell (12) investigated the mechanism of action of small molecule compounds (Erastin and RSL3) with a selective lethal effect on RAS mutant cell lines, and discovered that the two compounds could kill cancer cells by increasing intracellular iron content and accumulating oxidizing substances
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