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Patients should avoid making rapid dietary changes or severely restricting food intake beyond what naturally occurs from reduced appetite, as extreme caloric restriction can worsen gastrointestinal symptoms and compromise nutritional status
Intestinal glucose-induced calcium-calmodulin kinase signaling in the gut-brain axis in awake rats
The timeline for semaglutide to work depends partly on how quickly someone moves through these escalation phases, with most people reaching maintenance by week 17 at the earliest
Appetite regulation may become more stable
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