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We have eagerly awaited seeing the actual results since the sponsor company (Novo Nordisk) issued a press release in August that proclaimed a 20% relative reduction of cardiovascular death, heart attack or stroke, the primary endpoint of the trial
When to Suspect APD APD should be suspected when: Skin symptoms recur monthly despite standard dermatologic treatment Symptoms reliably worsen before menstruation Reactions appear after starting progesterone or progestins Antihistamines provide partial but not complete relief Related: Histamine Intolerance: What It Is & What to Do About It APD Causes and Risk Factors APD develops due to an autoimmune response to progesterone, though the exact mechanism of this hypersensitivity is not fully understood
These medications work by regulating appetite, slowing gastric emptying, and influencing the brains reward pathways
However, it may indirectly affect thyroid levels, especially for people with hypothyroidism
