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Cell Death Differ 2009
A high neutrophil to lymphocyte ratio found in critically ill patients with COVID-19 is associated with excessive ROS levels, that promote a cascade of biological events driving pathological host responses
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The increase of intracellular ROS is believed to correlate with the activation of nuclear factor (NF)-kappa B, a transcription activator linked to the elaboration of several cytokines (Figure 6)
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