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Based on available animal literature, the typical oral-to-parenteral effect-equivalence appears to require a 5-10 higher mass dose orally to match parenteral efficacy at systemic (non-GI) endpoints
Drug interactions and special situations Metformin and acid-suppressing meds can lower B12ask about periodic monitoring (NIH ODS)
More blood flow to injured tissue means faster delivery of oxygen, nutrients, and the building blocks needed for repair
In one 2019 study, both folate and vitamin B12 reduced levels of homocysteine while improving anemia status in a group of participants with relapsing-remitting multiple sclerosis
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